Naeemullah, Habibullah Shah, Amer Hayat Khan, Huma Gul, Khushnood Ali Baz.
Common organisms and their sensitivity, in open fractures of the extremities.
Pak J Surg Jan ;28(3):186-92.

Objective: The objective of the study was to identify common micro-organism present in open fractures and its sensitivity to antibiotics. Methodology: An observational descriptive study was designed, and was conducted from September 2009 to septeber 2010, in the District Headquarter & Teaching hospital Bannu, KPK, Pakistan. Fift y cases were thoroughly examined for life threatening conditions and after stabilization, a detailed history was obtained. All patients were prepared for surgical debridement under general anesthesia along with use of intravenous antibiotics and analgesics. A culture swab or tissue was taken from every patient and send for sensitivity. Results: It was found that 90% of the patients were infected. The incidence of infection increased with increase in exposure time and severity of injury. The most common organisms were Gram-positive 54% of Staphylococcus aureus. Over all antibiotic sensitivity were 78% of Cephalosporin, & 66% of Quinolones. Conclusion: All Gustilo type II and type III open fractures, reached to the hospital in more than 6 hours should be considered infected. Wound should be properly washed and specimen taken for culture and sensitivity. The patient should be started on intravenous fi rst generation cephalosporin and Aminoglycosides to cover both Gram-positive and Gram-negative organisms, till the availability of the culture and sensitivity reports.

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