Muhammad Israr, Fakhr Ul Islam, Niamat Ullah, Mukhtiar Ali.
Assessment of associated pain and complications in trus guided prostate biopsy in patients with and without local anesthesia.
Pak J Surg Jan ;28(3):172-6.

Objective: To asses the safety, effi cacy and complications of peri prostatic lignocain injection in trans rectal ultrasound (TRUS) guided biopsy of the prostate gland. Material and method: One hundred and ten male patients were selected for TRUS guided prostate biopsy. They were randomizely divided in to two equal groups i.e. 55 in group 1 and 55 in group 2. In group 1 local anesthesia (LA), 1% lignocain was injected in the peri-prostatic area and in group 2 the procedure was performed without local anesthesia. Eight to ten biopsy cores while in majority ten cores were taken. All the patients were asked to fi ll in the expected pain score on visual analogue (VAS) scale prior to the procedure. They also completed the actual pain score (VAS) experienced after the procedure. Complications occurred during the producer were recorded. Results: The age, mean PSA (prostate specifi c antigen) level were comparable in both groups The expected pain score was also comparable in both groups 5.20±1.4 in group 1 and 5.0±1.5 in group 2.In group 1 the mean actual pain score was3.20±1.6 and group 2 5.80±2.24. The complication rate was not signifi cantly diff erent in both groups. Conclusion: Periprostatic LA injection is safe, effective and should be routinely recommended to all patients undergoing TRUS biopsy of the prostate gland.

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