Mutahir A Tunio, Altaf Hashmi, Syed Shoaib Raza, Mansoor Rafi.
Metastatic prostate and renal cell carcinoma presenting as supra-clavicular lymphadenopathy: report of two cases.
Pak J Med Sci Jan ;27(5):1196-9.

Most metastases of cancers to cervical lymph nodes including supra-clavicular chain are from the head and neck primary tumors. Cancers metastasizing to the supra-calvicular lymph nodes from non-head and neck origin are rare. This occurs most frequently with lung, breast and esophagus. For prostate cancer, the non-regional lymph nodal involvment is very rarely reported. Similarly renal cell carcinoma presents mostly in advanced stage disease with involvment of non-regional lymph nodes is much less common. We present two cases of prostate and renal cell carcinoma who presented with initial manifestation of supraclavicular lymphadenopathy.

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