Masood Sadiq, Zubair Akram, Modasser Butt, JV De Giovanni, James L Wilkinson, Shakeel Q Ureshi.
Transcatheter Occlusion of Secundum Atrial Septal Defects with the self centering Amplatzer Septal Occluder initial experience.
Pak J Cardiol Jan ;12(3):61-6.

Between September 1999 to April 2001, 14 children and adults with age ranging between 343 years and weight ranging from 10-82 Kg were selected to undergo transcatheter occlusion of secundum atrial septal defect with self centering Amplatzer septal occluder. Echocardiographic criteria for exclusion were a defect >26mm or an insufficient septal tissue rim <4mm from either AV valve, coronary sinus or the right pulmonary veins. 11 of the 14 patients were successfully treated with the device. The defect diameter ranged from 621mm on T E.E and balloon stretched diameter varied from 16-30mm.11 devices ranging from 16-34mm were placed within the ASD and implanted. The procedural time ranged from 55165 minutes. 3 of the 14 patients could not be treated due to technical problems. 10 out of 11 treated patients demonstrated complete defect closure immediately after implantation of device as witnessed on colorflow Doppler examination while complete closure of defect was observed in all the patients after 24 hours. During follow up period of 8-737 days closure with no residual shunt has been demonstrated in all patients. Thus the Amplatzer septal occluder has proved to be effective and safe device for closing secundum atrial septal defects.

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