Shaila Anwar, Nabeela Shami, Naghmana Akbar, Shaheena Asif.
Induction of Labor by Prostaglandin PGE2 vaginal tablet in patients with previous Cesarean Section.
J Coll Physicians Surg Pak Jan ;12(4):208-11.

Objective: To evaluate the role of prostaglandin E2 vaginal pessary for induction of labor in patients who had previous caesarean section and presening with leaking. Design: A prospective study. Place and Duration of Study: This study was conducted in two phases. The first phase extended from July 1992 to June 1993 and was carried out at Sir Ganga Ram Hospital, Lahore. The second phase of the study was carried out at Jinnah Hospital, Lahore from March 1996 to May 1997. Materials and Methods: A total number of 42 patients at term with prior caesarean delivery and ruptured membranes as the presenting signs of labor were included. The study was updated and a total number of 20 patients were included. The inclusion criteria in the second phase were kept the same. Results: In the first phase of study, 35 (83.33% ) patients ended up with vaginal delivery while 7 (16.67%) patients had caesarean delivery. In the second phase of study, 17 (85.00 %) patients had vaginal delivery whereas 3 (15.00 %) patients ended up with caesarean section. None of the patients in both phases of the study had either dehiscence of the uterine scar or rupture of the uterus. Conclusion: Induction of labor by PGE2 vaginal pessary is a safe and feasible option in patients with prior caesarean section and ruptured membranes at term.

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