Zain Mehdi, Nadia Naseem, Safdar Sial, Rana Qaiser Mehmood, Aman-ur rehman, Imran Qadir, Nagi A H.
A study of renal tumours in tertiary care hospitals.
Biomedica Jan ;30(1):48-52.

Introduction: Renal cell carcinomas (RCC) comprise 90% of all renal tumours and are presage of poor outcome. Very little data has been published in Pakistan regarding the clinical and pathological mani- festations of the disease. Materials and Methods: A total of 50 cases presenting with different subtypes of RCC were selected from Allied Hospital Faisalabad and Sheikh Zayed Hospital, Lahore. Clinical details were obtained from the hospital records. The fresh nephrectomy specimens were further processed according to College of American Pathologists guidelines. Results: Mean age of the study population was 50.16 ± 11.982 years. Male to female ratio was 2.57:1. Left to right ratio was 1:1. Most tumours (n = 36, 72%) were located in the upper pole. Most common symptom was heamaturia (n = 38, 76%). Mean of the greatest dimension was 10.41 ± 4.22 cm. The most common stage of presentation was stage II (n = 21, 42%) and histological subtype was clear cell carci- noma (n = 37, 74%). Conclusion: Renal cell carcinoma, including its chromophobe variant, is a growing malignancy in Paki- stan. Delay in seeking medical care on the part of patient and inadequate facilities account for the tum- our growing to a larger size and more advanced stage of malignancy in our country.

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