Mirza Sultan Ahmad, Mubashra Ahmad, Ramlah Mehmood, Nazia Mahboob, Waqar Nasir.
Platelet Indices Among the Cases of Vivax Malaria.
Pak Paed J Jan ;39(1):39-44.

Objective: To ascertain the prevalence of thrombocytopenia and study changes in MPV(mean platelet volume) and PDW(platelet distribution width) in cases of vivax malaria. Design: Descriptive analytic study. Place and duration of study: Department of pediatrics, Fazle Omar Hospital, January to December 2012. Methodology: All patients from birth to 16 years age, who presented in Fazle- Omar hospital, Rabwah from January to December 2012 were included in the study. Hundred patients with other febrile illnesses were taken as control. Full blood counts were checked by Madonic CA 620 analyzer. SPSS 20 was used for data analysis. Results: One hundred and forty two patients were included in this study. There was no death or incidence of bleeding. Median platelet count was 109000/mm3. Thrombocytopenia was present in 108 (76.1%) patients. Severe thrombocytopenia was present in 10(7%) patients. Platelet counts of control group was significantly more as compared with study group.(p<.001) Median MPV was 8.70. MPV of study group was significantly more than control group.(p< .001) Median PDW was 11.30. There was no difference between PDW of study and control groups (p=0.246). There was no significant difference between platelet indices of male and female patients included in this study. Conclusions: Thrombocytopenia is a common in cases of vivax malaria. MPV of cases of vivax malaria is higher than control group.

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