Abu Talib, Khalid Hasan Khan, Naseema F Kapadia.
Study of changes in Oxygen Saturation, Blood Pressure, Cardiac Rhythm and Lignocaine level in IHD patients undergoing upper GI Endoscopy.
J Coll Physicians Surg Pak Jan ;12(7):391-4.

Objective: To assess the effects of endoscopy in ischaemic heart disease patients with special reference to oxygen saturation, blood pressure, cardiac rhythm, lignocaine level and the relation of serum lignocaine and oxygen saturation on cardiac events. Study: A prospective, matched, case-control study. Place and Duration of study : Department of Medicine, Dow Medical College, and Civil Hospital, Karachi, over a period of 6 months Patients and Methods: Sixty cases selected for endoscopy with dyspeptic symptoms were divided into two groups (30 in each group). study group comprised of ischaemic heart disease (IHD) patients and control group without IHD patients. Information regarding occupation, cardiorespiratory illness, addiction, medication etc., was obtained on a specially designed proforma and relevant investigations were carried out. Their pre-endoscopy oxygen saturation, cardiac rhythm and blood pressure were noted and monitored during and after the procedure till the changes that have taken place during procedure were returned back to their baseline level. At the end, blood sample was drawn for lignocaine level estimation. Results: Lignocaine levels remained in safe range in all patients but oxygen saturation dropped in IHD patients (10%) and they developed cardiac rhythm changes e.g., tachycardia and premature ventricular contraction (6.7%) and ST segment elevation (3.3%). Conclusion: Cardiac events in IHD patients can occur during the endoscopy, therefore, these patients should be monitored for oxygen saturation and supplementation. Lignocaine oropharyngeal gargles is the safe method of local anesthesia for upper GI endoscopy.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com