Arshia Javed, Haleema A Hashmi.
Misoprostol for induction of labour at term.
Pak J Surg Jan ;28(1):53-6.

Objectives: Th e purpose of this study is to assess the eff ectiveness of 50mg vaginal Misoprostol for induction of labour at term. Design: Retrospective observational study. Sett ing: Department of Obstetrics &Gynaecology, Liaquat National Hospital, Karachi, Pakistan from 1st January 2008 to December 2009. Methods: Two hundred and twenty one patients were analyzed; who were induced at 37 weeks gestation and onwards by using 50mg vaginal misoprostol repeated every 6 hourly for a maximum of 3 doses or initiation of active labour, to assess the effi cacy of the drug. Results: Th e results were analyzed by using SPSS version 13.0. Among 221 patients 161 (73%) delivered by vaginal route & 60 (27.1%) patient had caesarean deliveries. Out of these 91 (57%) patient, delivered within 8 – 12 hours. 22 (9.95%) patients had Meconium stained liquor. No case of uterine hyperstimulation and perinatal mortality observed. Conclusion: Vaginal Misoprostol was found to be safe and eff ective drug to use for induction of labour with least complications.

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