Muhammad Roshan Shaikh, Mahmood Saeed.
Lens Thickness in different types of Senile Cataract.
Pak J Ophthalmol Jan ;13(2):51-5.

A joint study was conducted at Dow Medical College and Jinnah Postgraduate Medical Centre, Karachi, to find out the relationship of lens thickness (anteroposterior diameter) with age, in different types of senile cataracts in 51 patients between 50 and 78 years of age. We found 19.5% cortical, 33.3% nuclear, 35.3% combined cortical and nuclear, and 11.8% posterior subcapsular cataracts. Histologically, the degenerative changes were, swollen cells, tiny globules, calcification, sclerosis, epithelial cell migration beneath posterior capsule and villous projections in posterior capsule. The anteroposterior thickness was significantly reduced in cortical and posterior subcapsular cataracts as compared to others. This was in contrast to normal (clear) lens thickness which showed a linear relationship of lens thickness with age. The morphological changes of lens did not show any relation with sex and profession of the patient.

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