Imtiaz Ali Shah, Saeed Ahmad Sangi, Seraj Ahmad Abbasi.
Bowen`s Disease.
Pak J Ophthalmol Jan ;14(1):37-8.

Two cases of Bowen`s disease of the limbal area, treated with surgical excision, have been followed for a period of two to two-and-a-half years. No recurrence occurred in both cases during the period of study. Following are the observations: 1. No association with other malignancies was seen in contrast to previous studies. 2. Both cases were under the age of twenty years. 3. No association with arsenic exposure was found contradicting older studies. On the basis of present results we recommend excisional biopsy of raised limbal lesions, unresponsive to topical medications including steroids, in all age groups.

CASE REPORTS: A 19-year-old male presented in January 1994 with slowly growing painless limbal mass on the right eye over the previous 12 months. He received topical steroids and decongestant drops for over 8 months, with no relief. On examination a 10mmsq mushroom-shaped mass was seen attached at 2 O clock limbus through a stalk. No history of trauma or surgery pointed to a spontaneous nature of the disease. The patient was a known case of cardiac valve disease. No other abnormality was found on systemic examination. Excisional biopsy was performed under local anesthesia. Histopathology confirmed the diagnosis of Bowen`s disease. No evidence of previous arsenic exposure was found by any route. The patient was followed-up till June 1996 with no recurrence and no other abnormal finding except cardiac disease.

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