Mahmood Saeed, J H Niazi, Nasir Zaman Khan, Saleh Memon, Faiz M Khan.
Carcinomata of Eyelids Presenting as Recurrent Chalazia.
Pak J Ophthalmol Jan ;14(3):99-103.

Histopathological examination of three patients with recurrent chalazia operated upon by us in 1996 at Jinnah Postgraduate Medical Centre PMC) Karachi, showed sebaceous cell carcinoma in two and squamous cell carcinoma in one. Sebaceous cell carcinoma was resected with 5 to 8mm and squamous cell carcinoma with 1.0cm of apparently healthy margin. Reconstruction of eyelids was done by different surgical techniques to get acceptable cosmetic and functional results. The two patients with sebaceous cell carcinoma did not show any recurrence in one to one-and-a-half-year of follow-up. The patient with squamous cell carcinoma did not have any sign of local recurrence but did develop one enlarged submandibular lymph node ten months after surgery. Fine needle aspiration biopsy was done and it proved to be a metastatic tumour. Since It is not feasible to undertake histopathological examination of the tissue after every chalazion surgery, It is mandatory in cases of recurrent chalazlon to have an early diagnosis for better management of life threatenlng tumours.

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