Tariq Mahmud Arain, Nazeer Ahmad Aasi, Tariq Mahmud Chaudhry, Muhammad Ayub Khan, Ejaz Latif.
Role of Debridement and Acyclovir in Herpes Simplex Dendritic Keratitis.
Pak J Ophthalmol Jan ;14(3):121-4.

To clarify the role of debridement in the optimal management of herpes simplex dendrltic keratitis, we conducted a randomized study comparing treatments with acyclovir alone and debridement followed by acyclovir. Forty patients were randomized into two treatment categories, twenty patients in each group. No statistically significant difference was observed between acyclovir treatment alone and debridement combined with acyclovir treatment with regard to healing time. Our results suggest that debridement combined with acyclovir appears to offer no advantage over acyclovir alone.

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