Mian Naushad Ali, Farsheed Sartaj, Faiz Mohammad, Aurangzeb Durrani.
Parenteral antibiotic before & during surgery can prevent post-operative infection.
J Pak Inst Med Sci Jan ;4(1,2):211-3.

A prospective randomized open study to assess the benefits of the use of prophylactic antibiotics in 296 consecutive cases who underwent clean surgery was carried out. These cases would, according to the local practice in vogue, have received a course of antiobiotics for a period of 5-7 days. The main purpose of the study was to find ways to combat such abuse of antibiotics. Out of nearly 300 cases who received prophylactic antibiotic, three patients developed wound infection. One needed local treatment while the other two needed continuation of antibiotics for 5 days. It would seem that only two doses of antibiotics is all that is required in patients undergoing `clean` surgery and not a 5 days course.

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