Ashba Anwer, Uzma Asif, Muhammad Asif Bhalli, Midhat Asif.
Gestational diabetes; screening in pregnant women.
Professional Med J Jan ;23(12):1465-70.

Objectives: To find the frequency of gestational diabetes in pregnant women using 50 grams glucose challenge test. Study design: a descriptive study. Place and duration: Department of Obstetrics and Gynecology, Lady Atchison Hospital, Lahore from August 2012 to August 2013. Methodology: Through non-probability convenient sampling, 200 pregnant women between 24-28 weeks of gestation were studied. All known diabetic patients were excluded from the study. Pulse, BP, weight and height were recorded and Body Mass Index was calculated. Physical and antenatal examination were done. Patients were given 50 gm glucose dissolved in 200 ml of water without any dietary preparation. Glucose levels were measured in venous plasma after one hour according to American Diabetic Association protocol. Blood glucose level more than 140mg/dl was diagnosed as screened positive and less than 140mg/ dl screened negative. The data analysis was analysed by SPSS 20. Results: Out of total 200 women studied, 28 (14%) had abnormal screening test while 172 (86%) had normal test. History of obstetric complications was noted in 10 (5%) women. PIH was noted in 19 (19.5%) and past history of GDM was present in 14 (8.13%). Mean age of patients screened positive was 25.03 ± 2.9 years. Gestational age of positive group ranged between 19 to 32 weeks. Mean gestational age was 26.17+3.37 weeks. Among screened positive women, 7 (25%) women were primigravida while 21 (75%) women were multigravida. Conclusion: Significant risk factor associated with GDM include family history of DM, maternal obesity, previous history of obstetric complications. Failure to recognize and treat the GDM results in maternal and fetal morbidity and mortality.

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