Ambreen Tauseef, Ayesha Akmal, Shahid Hasan, Amina Waheed, Anum Zafar, Ayesha Cheema, Qarib Mukhtar, Ayesha Malik.
Effect Of Energy Drink On Reaction Time, Haemodynamic And Electrocardiographic Parameters.
Pak J Physiol Jan ;13(1):7-10.

Objectives: To evaluate the cardiovascular effects and reaction time associated with energy drink in healthy medical students. Methods: In this randomized control design, a total of 30 healthy volunteers, 19–21 years of age of either sex were divided at random into three groups namely A, B and C. At the time of study, subjects were fasting overnight and were abstaining from caffeine for 48 hours. Baseline pulse and blood pressure were taken whereas heart rate, QTc interval and mean reaction time of each of three groups were measured by using power laboratory. The subjects of group A had consumed nothing while those belonging to group B and C were asked to consume 250 ml (1 can) and 500 ml (2 cans) of energy drink respectively and measurements were retaken after 1 and 2 hours interval. Statistical analysis was done using SPSS-19, and p≤0.05 was considered significant. Results: The pulse rate, heart rate, blood pressure and QTc interval increased significantly in group C at 2 hour as compare to group A and B. In group C, at 2 hours, pulse rate increased by 16.1% (p=0.001), systolic blood pressure increased by 9.5% (p=<0.001), diastolic blood pressure increased by 10.1% (p=0.002), heart rate significantly increased by 17.3% (p=0.015) and QTc interval prolonged by 12.4% (p=0.002). A decrease in mean reaction time was noticed by 20.0% (p=<0.001). Conclusion: Energy drink consumption increases the HR, BP, QT interval as well as performance. The more the energy drink consumed, the higher the changes are likely to be.

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