Ijaz Ahmed, Zarnaz Wand, Zaffar Ahmed.
Sensitivity of Staph. Aureus in childhood Atopic Dermatitis.
J Pak Assoc Derma Jan ;11(2):12-5.

Staph aureus plays an important role in Pathogenesis of atopic dermatitis; a chronic inflammatory disease. Toxins produced by these organisms act as exotoxins and aggravate the underlying disease. Staph aureus colonises the lesional skin of atopic dermatitis Successful management of atopic dermatitis has been reported with systemic antibiotic therapy. The study comprising of 50 patients, below the age of 12, was designed to determine the sensitivity pattern of staph Aureus in childhood atopic dermatitis. Swabs and scrapping obtained were sent for culture, microscopy and sensitivity. Staph aureus was cultured from the lesional skin of 44 patients 100% sensitivity was revealed for amoxycillin with clavulanate and quinolnes (p<0.001) Cephalosporins were next to follow with a sensitivity of more then 90% (p <0.001). Erythrocin was the least sensitive i.e 33% (p <0.001). It can be concluded from above study that amoxycillin with clavulnate is the first choice antibiotic in childhood atopic dermatitis, while quinolines despite 100% sensitivity are contraindicated for their ability to inhibit growth.

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