Mahjabeen Khan, Nadya Sultan Ali, Amyna Sajwani.
The Implication of Maternal Periodontal Disease and C Reactive Protein on Adverse Pregnancy Outcome.
J Pak Dent Assoc Jan ;21(1):16-9.

OBJECTIVE: To determine the role of periodontal disease in the development of adverse pregnancy outcome including low birth weight, preterm labor and to measure abnormal C reactive protein and its impact on adverse pregnancy outcome METHODOLOGY: This was a case control study. Periodontal disease was considered as 3 mm in 33 or more teeth.Adverse pregnancy outcome (APO)was defined as a singleton preterm birth and low birth weight.All mothers were interviewed and examined for periodontal disease. A blood sample of 3 ml was taken for C reactive protein assessment at the time of examination.Data was entered and analyzed on SPSS windows version 17 RESULTS: There were 600mothers observed for periodontal disease and c reactive protein and adverse pregnancy outcome. The adverse pregnancy outcome (APO) included preterm labour and low birth weight 29(21.5%).The birthweight < 2500 gms (low birthweight) was twicemore prone to developAPO due to Periodontal disease (PD) compared to controlswith birthweight> 2500gms.The gestational age before 37weeks (preterm)was 4 timesmore commonwith PDcompared to controls. CONCLUSION: Adverse pregnancy outcome is a possible complication ofmaternal periodontal disease.

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