Shazia Akbar Ansari, Rakhshanda Baqai, Hassan Mehdi, Ghulam Sughra Sahito, Gulnaz Ali.
Incidence of Bacteremia and Antibiotic Sensitivity Associated with Oral Surgical Procedures.
J Pak Dent Assoc Jan ;21(4):228-34.

OBJECTIVE The objectives of this research were to evaluate the incidence of bacteremia associated with oral surgical and invasive procedures and determine the antibiotic sensitivity pattern. METHODOLOGY A Total of 250 patients between 20 to 50 years of age were selected for this study who underwent different oral and maxillofacial surgical procedures for treatment of dental or periodontal disease. Clinical history was recorded from these patients. Blood samples were collected in blood cultures bottles with Tryptic Soy Broth (TSB) and incubated at 37°C for 7 days. After incubation sub culturing was done on a suitable media for bacterial growth and plates were incubated for 24-48 hours at 37°C. Colonies were identified by colony morphology, gram’s staining and standard biochemical tests. Antibiotic sensitivity was done by disc diffusion method. RESULTS Bacteremia was detected in 90 % of cases most commonly affecting the females. Tooth extraction (55%) was major cause of bacteremia. Major isolates were Staphylococcus aureus 56%, Escherichia .coli 25%, Pseudomonas aeruginosa 13%, Salmonella typhi 4% and Shigella spp.2%. Antibiotic sensitivity test revealed that all microbial isolates were sensitive to commonly used antibiotics. CONCLUSION Majority of the patients have post treatment bacteremia. Female gender and Tooth extraction, were associated with increased incidence of bacteremia. Most of the antibiotics were sensitive for different microorganisms isolated from oral surgical procedure.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com