Syed Asad Ali.
CENTRAL VENOUS CATHETER RELATED BACTEREMIA; Microbiologically confirmed, in intensive care unit pediatric patients.
Professional Med J Jan ;22(11):1514-9.

To characterize clinically, epidemically and microbiologically the episodes of confirmed bacteremia associated with intravascular catheters of patients in the pediatric intensive care unit. Study Design: An analytical, prospective study. Setting: Intensive care unit of Pediatric Hospital José Luis Miranda”. Period: January 2003 to December 2007. Methods: 453 patients. Rates, density of incidence, risk factors, static’s and mortality were determined and analyzed. Results: 96 patients developed bacteremia episodes and 90 (74%) had microbiological criteria. The risk factors associate were: to have multiple catheters, permanency with the catheter more than 7 days, parenteral feeding, prolonged mechanical ventilation, previous transfusions and surgical interventions. The isolations of coagulase negative staphylococci prevailed in 33 patients (36, 7%). The previous demurrage to the insert of the catheter was of 4,0 ± 9,4 days for the healthy ones and 11, 6 ± 24,6 days in the sick persons (p = 0,000); the definitive demurrage was of 56,1 ± 62,4 days in the sick persons versus 24,6 ± 31,7 days in the healthy ones (p = 0,000). The mortality of the second group was superior (26%). Conclusions: Multiple dependent and independent factors exist on which actions should be focused to prevent and to diminish the mortality by bacteremias associated with catheters in children admitted in intensive care units.

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