Ashraf M Z, Khan I A, Zeeshan N, Chaudhry M A.
Association Of Blood Group \'A\' With Ischemic Heart Disease.
Biomedica Jan ;33(2):131-5.

Background and Objectives: The Pakistani populace has one of the most noteworthy dangers of ischemic heart disease (IHD) on the planet. Epidemiological information with respect to relationship between ABO blood groups and danger of coronary illness has been conflicting. The objective of this study was to comprehend the recurrence of blood group A in IHD patients in our populace and to decide the relationship of blood group A with ischemic coronary illness in our setting and hopefully improve public knowledge about risk factors for IHD. This case control study was carried out at Army Cardiac Centre, Combined Military Hospital, Lahore, Pakistan from October-December 2014. Methods: Total Sample of 408 patient medical records was included in the study. Information was entered and analysed by utilizing Statistical Package for Social Sciences (SPSS) version 20.0 programming for Windows. Results: Prevalence of blood group ‘A’ was significantly higher among IHD group i.e. 25.5% as compared to controls i.e. 15.2%,(Odds Ratio (OR) = 1.91, 95% confidence interval (CI) 1.16 to 3.13, p = 0.01) recommending there is a profoundly noteworthy relationship of blood group "A" with IHD. Conclusion: The Pakistani cohort researched in this study plainly demonstrates blood group phenotype A is connected with an increased risk for IHD. This, by all accounts seems free of traditional cardiovascular risk variables. Along these lines, it is suggested that blood group "A" ought to be incorporated into non-modifiable hazard elements of ischemic coronary illness in our populace.

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