Hussain S, Naseem N, Nagi AH.
Age, gender and site distribution of salivary gland tumours reported at tertiary care hospitals.
Biomedica Jan ;32(3):160-4.

Background and Objective: Salivary gland tumours constitute 3-10% of all head and neck tumours. Pleomorphic adenoma (PA) is reported to be commonest benign neoplasm of salivary glands in Pakistan constituting 80–90% of all benign salivary gland tumours while mucoepidermoid carcinoma (MEC) and adenoid cystic carcinoma (AdCC) constitute 44% and 31% of all malignant salivary gland neoplasms. The objective of this study was to determine the distribution of these salivary gland tumours with respect to age, gender and site involved in the local population of Lahore. Method: This descriptive study was conducted at the Department of Morbid Anatomy and Histopathology/Oral pathology, University of Health Sciences Lahore, Pakistan. A total of 182 cases, reported at King Edward Medical University/Mayo Hospital, Sheikh Zaid Hospital, Fatima Jinnah medical University/Ganga Ram Hospital Lahore, were included. The clinical data was retrieved from records of respective hospitals (from January 2012 to September 2015). Results: Age, gender & site distribution, most frequently encountered in the current study, were 3rd – 5th decades of life, female predominance (1.3:1) and parotid gland (51.6%) involvement respectively. The mean age for PA, AdCC and MEC was 35.61 ± 15.69 years, 32.96 ± 14.88 years and 44.06 ± 13.87 years respectively. Regarding gender distribution, female predilection (1.5:1) inPA, male predisposition in AdCC (1:1.1) and equal gender distribution (1:1) in MEC was noted. Parotid gland was the predominant site affected by PA (57.3%) and MEC (70.8%) while minor salivary glands (87%) were affected byAdCC. Also noted in the current study was the fact that adenoid cystic carcinoma (18.7%) is slightly more common than mucoepidermoid carcinoma (13.2%) in this population. Conclusion: It is concluded from the current study that salivary gland tumorsin the study population affect a younger age group with slight female predilection. The main gland affected by PA and MEC is parotid while minor salivary glands (mainly mostly palate)are involved by AdCC. Also, it can be concluded that AdCC is slightly more common than MEC in local population of Lahore.

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