Afroza Abbas, Humaira Akram, Bushra Farooq.
Comparision of hemodynamic changes caused by 2 units versus 5 units of oxytocin during elective caesarian section under spinal anaesthesia.
Esculapio J Services Inst Med Sci Jan ;9(4):168-70.

Objective: To compare the efforts of 2 units and 5 units bolus doses of oxytocin on heart rate and mean arterial pressure during elective caesarian section under spinal anaesthesia. Material and Methods: Randomized control study, conducted over 6 months period on 150 patients at Maula Baksh Teaching Hospital Sargodha by dividing into 2 groups (groups A & group B), through lottery method for randomzation of oxytocin allocation. Results: In our study, majority of the patients i.e. 45.33%(n=34) in Group-A and 38.67%(n=29) in Group-B were between 26-30 years of age, mean + SD was calculated as 27.85+3.54 years., while 60%(n=45) in group A and 56%(n=42) in group B were between 37-39 wks of gestation, mean + SD was calculated as 38.63+4.61wks. Blood loss in both groups shows insignificant difference by recording 187.43+18.65 ml in Group-A and 194.24+21.47 ml in Group-B, comparison of tachycardia in both groups was done which shows 32%(n=24) in Groups-A and 61.33%(n=46) in Group-B while which shows a significant difference in both groups while hypotension was recorded as 4%(n=3) in Group-A and 17.33%(n=13) in Group-B, p value was calculated as <0.01. Conclusion: We concluded that frequency of tachycardia and hypotension in patients administered with 2 IU bolus dose of oxytocin is significantly lesser as compared to 5IU bolus dose and there is no difference in the incidence of postpartum haemorrhage.

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