Saadia Sharif, Ameelia Sadaqat, Shamayela Hanif, Rabia Noor.
Single Dose Methotrexate in Ectopic Pregnancy.
Esculapio J Services Inst Med Sci Jan ;7(2):5-7.

Objective: To evaluate the efficacy of a single dose of MTX for ectopic pregnancy management. Material and Methods: 37 patients were carefully selected according to inclusion criteria. β-hCG was done at diagnosis and at day 7. A single IM dose of MTX was given & patients were kept admitted till recovery. Results: Out of the 37 patients, 5 patients had ruptured ectopic pregnancy in spite of taking MTX. 26 had single dose and had a time of ectopic pregnancy resolution averaging 26.4 days. The remaining 6 patients received an additional dose of MTX with the time resolution of 35 days. Conclusion: The successful medical management of ectopic pregnancy was seen in 26 patients (81%) in whom β-hCG levels became negative after administration of single MTX.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com