Fehmida Naheed.
Bromocriptine: Effect on Galactorrheic, Hyperprolactenaemic women.
J Coll Physicians Surg Pak Jan ;9(1):28-31.

A prospective observational study was designed to determine the response to Bromocriptine (Parlodel) therapy in terms of occurrence of pregnancy and its outcome in women who had infertility associated with galactorrhea and hyperprolactinaemia. A total of 29 infertile women found to have galactorrhea and hyperprolactinaemia. Out of them 40% had primary infertility and 60% were of secondary infertility. About 27% patients had associated menstrual problems. After excluding or treating other causes of infertility Bromocriptine therapy was instituted with the minimum dose and slowly building up the requried dosage. In 73% (21/29) patients Bromocriptine was prescribed in a dosage of 5 mg per day and 7.5 mg was given to the rest of the cases. Tolerance to Bromocriptine was quite remarkable. Pregnancy was achieved in 48% (11/23) cases, in 36% cases of primary infertility and 64% of secondary infertility. About 82% (9/11) conceptions occurred within 2 to 6 months of therapy and of the 11 pregnancies 9 ended as successful term deliveries. Clomiphene citrate was given to 27% (3/11) patients due to ovulatory dysfunctions.

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