Tabassum Mahboob.
Effect of chronic ethanol administration on systolic blood pressure in Rats: Role of electrolyte alterations.
J Coll Physicians Surg Pak Jan ;9(4):166-70.

The role of alcohol drinking habits in the precipitation of hypertension is often described in clinical studies. Parallel studies in experimental animals are indicative of various hormonal regulations and Na-K-ATPase. The present studies concerns the sex differences of electrolyte homeostasis and systolic blood pressure in chronic ethanol treated rats. Chronic administration of ethanol raises systolic blood pressure which was associated with an increased sodium and potassium in red cells, decreased sodium, potassium calcium and magnesium in plasma, increased calcium in heart and kidney tissue and decreased magnesium in kidney tissue. Chronic ethanol induced hypertension and changes in red cell and tissue electrolytes were greater in male than female rats.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com