Abdul Rehman, Sultan Ahmed Shah, Khan R A.
Correlation of Technetium-99M Tetrofosmin Perfusion Imaging with Coronary Angiography in patients with known or suspected Coronary Artery Disease.
Pak J Cardiol Jan ;13(3-4):77-84.

This study correlated the results of Single Photon Emission Computed Tomographic (SPECT) imaging with technetium-99m tetrofosmin with those of coronary angiography in patients with known or suspected coronary artery disease. Total 65 patients were included in this study and divided in to two groups, the study group and the control group. 35 patients included in study group and 30 patients in control group. All the patients underwent stress/ rest imaging with technetium tetrofosmin and coronary angiography. SPECT images were divided in to five segments per patient and > 70% occlusion of coronary arteries were considered to be significant. 95 perfusion defects were noted and 70 coronary arteries were involved in diseased process. Left anterior descending artery (LAD) was involved in 70 % of cases and right coronary artery (RCA) in 66%. In Tc. Tetrofosmin study the fixed defect was more common in left ventricular apex and reversible ischemia and mixed defect in inferior wall. Regarding sensitivity RCA 87%, LAD 85% and circumflex 70% and specificity 93% in circumflex, 83 % in RCA and 75 % in LAD and the p-value is <0.01.

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