Jamaluddin Syed, Aftab Ahmed Khan, Erum S Khan.
Micro-CT evaluation of mineral trioxide aggregate and bioactive glass as apical seal.
Pak J Surg Jan ;32(4):239-44.

Purpose: The purpose of this study was to determine and compare the ability of bioactive glass (BAG) with mineral trioxide aggregate (MTA) as a potential apical sealer. Methods: Recently extracted sixty human premolars single-rooted teeth for orthodontic reasons were selected. Matched pairs were separated into two groups (n=30). Teeth of the first group were obturated with Thermafil whereas the second group obturated with BAG. Micro CT was performed and reconstruction of the specimen image was done by using the cone-beam technique. Results: Bioactive glass (BAGs) when compared to the mineral trioxide aggregate (MTA) as an apical seal found to be less porous. There were virtually no marginal linear gaps when analyzed by Micro CT. The apical thirds filled with MTA had a significantly lower 3D void volume (P< 0.05) when compared with apical thirds filled with BAG. Clinical significance: The results of this in-vitro study suggest potentiality of bioactive glass as a root canal sealer.

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