Ps Mahar, Nasir Memon, Sami Memon, Faisal Faheem.
Role of Oral Rifampicin in Chronic Central Serous Chorioretinopathy.
Pak J Ophthalmol Jan ;34(1):3-8.

Purpose: To determine the improvement in visual acuity and central macular thickness in patients with chronic central serous chorioretinopathy (CSCR) with oral Rifampicin. Study Design: Quasi experimental study. Place and Duration of Study: Isra Postgraduate Institute of Ophthalmology, AlIbrahim Eye Hospital, Karachi. From September 2015 to December 2016. Material & Methods: Ten eyes of 10 patients having chronic CSCR of more than 6 months duration were prospectively treated with oral Rifampicin 450 mg in single oral dose for 3 months duration. All patients were followed-up for 12 months. Results: Ten eyes of 10 patients were included in the study. The gender distribution showed 8 male (80%) and 2 female (20%) patients. There were five right and five left eyes. Mean age of our patients was 40.10 ± 5.1 years (Range 34 ? 46 years). Mean duration of patient?s ocular symptoms was 9.4 ± 2.9 months with range of 6 ? 14 months. Patient?s visual acuity improved at 3 months follow-up. Mean Pre-treatment central macular thickness was 350 ± 82.3 µm improving to 232 ± 54.3 µm at 3 months treatment. Conclusion: All patients with chronic CSCR of more than 6 months duration showed improvement in their vision and central macular thickness with oral Rifampicin taken for 3 months.

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