Muhammad Saqib Habib, Shafat Khatoon, Aijaz Ahmed Sand.
Hyperuricemia; a Risk Factor for Development OF Hypertension in Pakistani Community.
Professional Med J Jan ;25(3):381-6.

Objectives: To determine the association of hyperuricemia with hypertension. Study Design: Case-control study. Place and Duration of Study: Out-patient department of Fuji foundation hospital, Rawalpindi. The study conducted over a period of six months from 1st February 2012 till 31st July 2012. Methodology: 268 patient were selected for study and divided into two groups on the basis of presence or absence of hypertension (group 1 comprised of newly diagnosed hypertensive patients and group 2 comprised normotensive individuals). Each group comprised 134 patients fulfilling inclusion/ exclusion criteria. Serum uric acid levels were checked and compared in both groups. Results: In hypertensive group, the minimum age was 20 years and the maximum age was 100 years with a mean age of 50.76. Minimum uric acid level was 193/liter?mol and maximum uric acid level was 608 ?mol/L with a mean of 316.87. In non-hypertensive group, minimum age was 20 years and the maximum age was 80 years with a mean age of 47.84. The minimum uric acid level was 125?mol /L and the maximum was 404?mol/L with a mean of 273.24. The P-value was 0.000 which means that the difference between the two groups was statistically significant. Conclusion: There is statistically significant association of hyperuricemia with hypertension. More studies are recommended to establish this fact.

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