Ilyas Saeedi M, Sher Rehman, Nusrat Ilyas.
Wilson`s Disease.
J Postgrad Med Inst Jan ;16(2):223-6.

In this first family from Peshawar, both mother and father were normal with the only laboratory abnormality was slightly increase urinary copper excretion. Amongst the children two suffered from the disease. Another family was from district swat where mother has increase excretion of urinary copper. Amongst the children one son died from the hepatitis at the age 6 the other has neurological presentation with difficulty in walking and had cirrhosis liver. The third family was from District Swat where the mother had increase excretion of urinary copper with the rests of test being normal. One of the child suffered from full blown Wilson`s disease with both hepatics and neurological signs and sentences while the younger patient age 4 is asymptomatic with low serum cearuloplasmin level of < 0.174 and increase urinary copper excretion.

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