Naheed Haneef, Sultan Ahmed Shah, Khan R A.
Comparison of Gated Blood Pool Ventriculography with Echocardiography and Contrast Ventriculography for Left Ventricular Ejection Fraction determination in post Myocardial Infarction patients.
Pak J Cardiol Jan ;14(1):3-11.

Obective: We compared the efficacy of gated blood pool (GBP) ventriculography with echocardiography and contrast ventriculography for measurement of left ventricular ejection fraction (LVEF) in patients with myocardial infarction. Methods: Gated blood pool ventriculography (invivo technique) and echocardiography were performed in 30 patients at least after 24 hours but within 48 hours of contrast ventriculography. Echocardiographic methods included: (1) Subjective (visual) estimation of LVEF from 2 dimensional (2D) echocardiography. (2) 2D directed M-mode (Cubed method) echocardiography. Single plane cine ventriculographic ejection fractions were calculated using Dot calibration method. Results: The comparison of GBP ventriculographic LVEF with contrast ventriculographic LVEF and 2D echo estimated LVEF revealed no significant difference in their mean ejection fraction (44.04 ± 11.93 vs 48.46 ± 12.78% p = NS) & (44.04 ± 11.93 vs 47.38 ± 13.06%, p= NS) respectively, while comparison of GBP LVEF with 2D directed M-mode (cubed method) echocardiography revealed highly significant difference in their mean EF (44.04 ± 11.93 vs 61.7 ± 15.65%, p < 0.01). GBP LVEF has statistically significant correlation with contrast ventriculographic (r = 0.86) and 2D echo estimated (r = 0.77) LVEF, while has poor correlation (r = 0.57) with cubed formula from 2D echo. Conclusion: GBP ventriculography can be utilized accurately for determination of ejection fraction in post myocardial infarction patients for diagnostic and prognostic evaluation.

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