Abdul Haleem Shah, Abdul Hameed, Gul Majid Khan.
Fermentative production of L-Lysine: Fungal Fermentation and Mutagenesis-II a review.
Pak J Pharm Sci Jan ;15(2):29-35.

Lysine has been recognized as one of the most deficient essential amino acids. It is an economically important food and feed supplement. It has also got various pharmaceutical applications in the formulation of diets with balanced amino acid concentration and in amino acid infusions. Chemical, enzymatic and fermentation processes have been used to synthesize lysine. The objective of this review is to outline the research work of various scientists which provide important and beneficial information regarding the production of lysine through fungal fermentation and mutagenesis. Moreover, methods to improve the total yield and quality of lysine are also presented.

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