Mahmood Sheikh, Sheikh Abdul Khaliq, Iqbal Azhar, Ejaz Mohiuddin.
Impact of Physical Activity on Fasting, Random Blood Sugar and HbA1C in Type - II Diabetic patients.
RADS J Pharm Pharmaceut Sci Jan ;8(2):98-105.

Objective: Aim of the study is to evaluate the impact of physical activities on fasting, random blood sugar and HbA1C on patients getting treatment with different systems of medicine. Methods: Prospective cross sectional study was conducted in outpatient facilities of Karachi from July 2017 to July 2018 with treatment duration of at least one year. 195 type - II Diabetic patients with confirm diagnosis enrolled in the study. Study has three arms of anti-diabetic treatment; herbal, homeopathic and allopathic. Outcome measures are Fasting Blood Sugar (FBS), Random Blood Sugar (RBS) and HbA1C with and without exercise. Results: In exercise group, mean reduction of FBS in patients; Allopathic=138.31+-46.11 mg/dl, homeopathic=100+-00 mg/dl, herbal=121.11+-19.64 mg/dl, combination=135.20+-40.85 mg/dl. Mean reduction of RBS; Allopathic=186.25+-58.77 mg/dl, homeopathic=140.00+-00 mg/dl, herbal=198.88+-49.60 mg/dl, combination=231.90+-64.10 mg/dl. Mean reduction of HbA1C; Allopathic=7.53+-1.97%, herbal=6.47+-0.335%, combination=7.21+-1.147%. In patients not doing exercise, mean reduction of FBS in patients; Allopathic=183.80+-85.49 mg/dl, homeopathic=119.00+-47.71 mg/dl, herbal=131.00+-17.68 mg/dl, combination=134.37+-49.88 mg/dl. Mean reduction of RBS; Allopathic=240.08+-92.76 mg/dl, homeopathic=163.00+-32.33 mg/dl, herbal=193.66+-46.42 mg/dl, combination=212.67+-87.21 mg/dl. Mean reduction of HbA1C; Allopathic=8.89+-2.04%, homeopathic=6.40+-00%, herbal=6.54+-0.398%, combination=7.10+-1.53%. FBS is significantly better controlled by allopathic system compare to homeopathic (p=0.004), herbal (p=0.0001), combination (p=0.0001). RBS is significantly better controlled by allopathic system compare to homeopathic (p=0.006), herbal (p=0.017). Homeopathic system significantly better control RBS compare to combination treatment (p=0.036). Conclusion: Physical activities and exercises can provide better control on FBS, RBS HbA1C. Allopathic and combination systems of medicine have better glycemic control in type - II Diabetes Mellitus patients involve in physical activities.

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