Neelam Noreen Halimi, Ijaz Hussain, Muhammad Ilyas, Shahana, Syed Israr Muaziz, Syeda Sadia.
Comparison of hemodynamic changes with the insertion of laryngeal mask airway insertion and endotracheal intubation in laparoscopic cholecystectomy.
Pak J Surg Jan ;36(2):161-6.

Objective: Comparison of Hemodynamic changes with the insertion of Laryngeal Mask Airway (LMA)and Endotracheal (ETT )Intubation in laparoscopic cholecystectomy. Material and Methods: A prospective randomized control trial was conducted at anesthesia department Khyber teaching Hospital Peshawar form February 2019 to September 2019. 144-patients from age 18-60 years, having ASA grade I/II, with BP of 110/70 to 120/80 mmHg on admission undergoing laparoscopic cholecystectomy were included in this study and were randomized via lottery methods into two groups. Group-A patients will have LMA insertion while group-B patients will have ETT insertion. Informed consent was taken before surgery from each patient. Patient having GERD and compromised pulmonary function were excluded from study. Changes in blood pressure and heart rate were recorded in both groups. Group-A, insertion of LMA and Group-B. Endotracheal intubation, data were compiled and analyzed with SPSS 20. Chi-square test was applied to compare changes in both groups, taken P <= 0.05 as significant. Results: The ETT group consisted of 29 males and 43 females while the LMA group had 32-males and 40-females. The maximum and minimum ages in the ETT and LMA groups ranged from 22 to 60 years and 21 to 60 years respectively. The mean weight of subjects was 67.3 kg in LMA group and 65.3 in ETT group. In terms of demographic data such as age, sex, weight and ASA classification, no substantial difference between the two groups was observed. Good hemodynamic response was calculated at 10-minutes and LMA group showed good hemodynamic response in 79% (57) of patients while in ETT good hemodynamic response was shown in 68%(49) of patients. This difference was statistically significant. Conclusion: Good hemodynamic response was calculated at 10 minutes and LMA group showed good hemodynamic response in 79% (57) of patients while in ETT good hemodynamic response was shown in 68% (49) of patients. This difference was statistically significant. The use of LMA should be encouraged in routine cases, especially in cases with cardiac issues.

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