Shahzadi Sumbal Ghazi, Muqadar Shah, Noshina Riaz, Fatima Hashmi, Jai Krishin, Asma Khan.
Single Iron supplementation versus combined Vitamin a and Iron supplementation in treatment of Iron Deficiency Anemia in children less than 5 years visiting tertiary care hospital of Islamabad: a randomized Control Trial.
Isra Med J Jan ;12(2):56-9.

Objective: To compare Vitamin A supplementation along with iron supplementation and iron supplementation alone in treatment of iron deficiency anemia in terms of mean Hb improvement in children less than 5 year. Study Design: Randomized Controlled Trial Place and Duration: Department of Pediatrics, Pakistan Institute of Medical Sciences Hospital, Islamabad from 1st July 2016 to 31st December 2016. Methodology: Total of 80 diagnosed cases of iron deficiency anemia patients were enrolled with 40 in each group. Patients were randomly assigned into group-A (iron and Vitamin A supplementation) and group-B (iron supplementation only) by using simple random sampling. A baseline venous sample of 5ml was taken to obtain patient`s Hb, MCV, MCHC, Ferritin and Iron. Follow-up blood samples were obtained of patients in both groups for Hemoglobin level after two months. Results: Both groups were comparable for age and gender and baseline Hemoglobin levels which were 8.9 + 0.36 in Group A and 8.8 +0.38 in Group B (iron supplementation only). There was significant improvement in hemoglobin level in group A compared with group B, mean hemoglobin 11.9 + 0.99 in Group A and 9.6+1.03 in Group B respectfully, p-value was 0.00. Conclusion: Addition of Vitamin A along with iron supplementations significantly improve hemoglobin levels in iron deficiency anemia patient in pediatric age group less than 5 years.

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