Saima Mukhtar, Iram Qamar, Javeria Latif, Sobia Niaz, Rahat Naseem, Mah-e Jabin Sear.
Relationship of vitamin D levels with systolic, diastolic and mean arterial pressure in male residents of Lahore.
J Med Sci Jan ;28(2):112-6.

Objectives: To correlate vitamin D levels with severity of hypertension. Material and Methods: This study was conducted from September 2016 to December 2016 which comprised seventy-five male subjects from outdoor department of Lahore General Hospital, Lahore Pakistan, and divided into stage I and stage II hypertension groups and healthy attendants were taken as controls. Newly diagnosed hypertensive male patients were included and patients having secondary hypertension, low vitamin D, known kidney, liver, thyroid, parathyroid or cardiac disease were excluded. Blood pressure of subjects was measured using a mercury sphygmomanometer and blood samples for analysis of vitamin D levels were taken. Results: Subjects included had a mean age of 39.97 +- 8.24 years. Mean vitamin D levels (ng/mL) were 35.99 +- 8.08, 28.71 +- 10.85 and 28.12 +- 9.94 in controls, stage I hypertension and stage II hypertension groups respectively. Mean systolic blood pressure (SBP) and mean diastolic blood pressure (DBP) was 110.72 +- 5.59 mm Hg 73.24 and +- 3.35mm Hg in controls, 131.20 +- 8.83 mm Hg and 91.80 +- 5.86 mm Hg in stage I HTN and 144.28 +- 19.28 mm Hg and 103.40 +- 12.05 mm Hg in stage II HTN group, respectively. Both SBP and DBP were inversely related to low 25 (OH) D levels (r=-0.289 & -0.315) respectively.Conclusion: There is an association suggestive of increased SBP, DBP and mean arterial pressure with lower levels of Vitamin D.

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