Rizwana Muzaffar, Zarfishan Tahir.
Diagnosis of Diabetic Autonomic Neuropathy - A multivariate approach.
Biomedica Jan ;19:51-6.

Seventy five (75) diabetic patients in the age range of 30 - 65 years were evaluated for autonomic nervous system affections, by using 3 bed side tests to detect cardiac neuropathy. Out of a total of 75 cases, 38 were symptomatic for diabetic autonomic neuropathy (DAN), while 37 were asymptomatic. 37 healthy age matched controls were also included in the study. Amongst the study population, the abnormality of the parasympathetic division i.e. valsalva response and heart variation during deep breathing were found to be greater than the sympathetic component i.e. blood pressure response to standing. Similarly the frequency of abnormality in the values of autonomic function tests were greater in the symptomatic diabetic group than the asymptomatic diabetic group. This study also proved that the frequency of DAN was directly proportional to the duration of disease.

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