Mazhar Iqbal, Khalid Rashid, Zia ul Islam, Asadullah Khan.
Incidental diagnosis of early Carcinoma Gall Bladder in Chronic Cholecystits with Cholelithiasis.
J Surg Pak Jan ;8(2):23-5.

The objective of this study was to find out the number of incidental early carcinoma gall bladder in chronic cholecystitis with gall stones and to evaluate the age and sex distribution of early carcinoma of gall bladder in our set up. The study was conducted in ward 3 Jinnah postgraduate Medical Centre Karachi for five years from January 1997 to December 2001. A total 604 Patients diagnosed as chronic cholecystitis with gall stones in surgical outpatients department, were admitted in ward 3 after carrying out all the necessary investigations for gall stones disease and underwent cholecystectomy. Histopathology was done at The Basic Medical Sciences Institute Jinnah Postgraduate Medical Centre Karachi, and in 24 patients we incidentally found on histopathological report, an early carcinoma gallbladder. Incidental diagnosis of carcinoma gall bladder with gall stones in our study was 3.97%. Carcinoma gall bladder was more common in females (91.67%). Male to female ratio was 1: 11. and more common around 50 years of age. Incidental diagnosis of carcinoma gall bladder with gall stones is very high in our setup (3.97%) and relatively in younger age (41 to 60 years) group in our study. The role of early cholecystectomy to prevent and cure carcinoma gall bladder in early stages is essential even silent stones should not be ignored.

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