Salman Tahir Shafi, Mohammad Saleem, Roshina Anjum, Wajid Abdullah, Tahir Shafi.
Lipid abnormalities in hospitalized patients with chronic kidney disease not on hemodialysis.
J Sharif Med Dent Coll Jan ;2(01):3-6.

Objective: To assess the frequency of lipid abnormalities in chronic kidney disease (CKD) patients in local population. Methodology: All patients with CKD who were admitted to nephrology ward of Sharif Medical City Hospital over a 3 month period and who gave informed consent for the study were included. Fasting lipid profile was obtained. Results: A total of 124 patients were included in the study. Mean age of patients was 49.9+14 years. Of all patients, 72 (58.1%) were males and 52 (41.9%) were females. Hypertension, diabetes mellitus and cardiovascular disease were present by history in 84.8%, 67.2% and 28% respectively. Mean serum creatinine was 7.25+3.4 mg/dl and mean estimated glomerular filtration rate (eGFR) was 11.3 11.9 ml/min/1.73m2. Mean serum cholesterol was 170.9 +51.7 mg/dl, mean serum high density lipids (HDL) was 49.1+29.8 mg/dl, mean serum low density lipids (LDL) was 89.1=27.5 mg/dl and mean serum triglycerides were 115.4-36.4 mg/dl. High cholesterol, high LDL, low HDL and high triglycerides were present in 15.2%, 27.9%,81.1% and 1.8% of all patients respectively. Conclusion: Lipid abnormalities are common in CKD patients not on hemodialysis. Low HDL is the most common abnormality in our patient population. Keywords: Chronic kidney disease. Diabetes mellitus. Estimated glomerular filtration rate.

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