Roshina Anjum, Mohammad Saleem, Uzma Ihsan, Salman Tahir Shafi, Tahir Shafi.
Dermatological manifestations in patients on hemodialysis experience at Sharif Medical City Hospital.
J Sharif Med Dent Coll Jan ;2(02):46-9.

Objective: The objective of this study was to determine the frequency of dermatological manifestations in patients on hemodialysis at Sharif Medical City Hospital. Methodology: A random sample of 50 patients, who were 18 years or older and had end stage renal disease on maintenance hemodialysis, were selected. Symptoms attributed to abnormal dermatological manifestations including pruritus, dry mouth and hair loss were inquired. Skin, oral cavity, hair and nails were examined after proper exposure by a qualified dermatologist. Results: A total of 50 patients were included in the study. Mean age of patients was 43.5+13.7 years. Out of 50 patients, 16 (32%) were male and 34 (68%) were female. Mean number of dermatological abnormalities was 4.1+1.1 in all patients. Cutaneous, oral, nail and hair abnormalities were noticed, 20%, 50% and 42% of all patients respectively. Xerosis (58%), pigmentary changes (46%), pruritus (32%), cutaneous fungal infections (26%), acanthosis nigricans (38%), xerostomia (10%), half and half nails (26%), koilonychia (16%) and sparse body hair (20%) were the most common abnormalities. There was significant positive correlation between age of patients and number of dermatological manifestations (r=0.37, p 0.009). Conclusion: Cutaneous and mucosal abnormalities were common in patients on hemodialysis. Older age was associated with higher number of abnormal findings. Keywords: Hemodialysis. End Stage Renal Disease. Xeroxes. Pruritus.

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