Syed Farhan Ahmed, Imran Idrees Memon, Mohammad Asim, Mohammad Rashid, Waqas Ahmed, Aziz Abdullah.
Evaluation of Alfuzosin efficacy in reducing postoperative flank pain during voiding in patients with ureteric stent.
Rawal Med J Jan ;46(1):79-82.

Objective: To evaluate the efficacy of alfuzosin in reducing postoperative flank pain during voiding, in patients with ureteric stent. Methodology: This randomized control trial was conducted at Urology Department, Liaquat National Hospital, Karachi from April to October 2014. Participants of the study were divided into Group A receiving alfuzosin and Group B receiving placebo for 6-weeks duration. Postoperatively, stent-related flank pain during voiding was assessed at the end of the sixth week and a mean score of pain was calculated. SPSS version 21 was used to analyze data, with p<= 0.05 taken as significant. Results: A total of 70 patients with a mean age of 33+-7.67 years were enrolled in the study. Mean pain score in alfuzosin group was 3.16+-1.48 and in the placebo group 5.89+-1.52. Among alfuzosin group, efficacy was observed in 24 (68.57%) patients while in the placebo group, in only 5 (14.28%) patients (p<0.01). Conclusion: The use of Alfuzosin in patients with unilateral stenting significantly improved stent related urinary symptoms; especially irritative symptoms like pain and flank pain during voiding.

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