Muhammad Munawar Hussain, Nawaz Anjum, Muhammad Qaisar Pervaiz, Faiza Farooq, Syed Amir Gillani.
A Systematic Review on Comparison of Diagnostic Accuracy of Ultrasound and Computed Tomography in Right Upper Quadrant Pain.
Pak J Radiol Jan ;31(1):28-35.

In this systematic review we aimed to explore relevant data on efficacy of the Ultrasound and Computed Tomography (CT) scan regarding Right Upper Quadrant (RUQ) pain, studied in recent decades. For this study we collected data of different regions to evaluate the diagnostic accuracy of CT and Ultrasound for RUQ pain. Methodology: Research was conducted with the help of keywords. Two hundred and sixty-two articles were found at initial stage. We included demographic information like the sample size, author information, and area of the study in table form. We also observed the CT and Ultrasound findings regarding sensitivity, specificity, true positive (TP), false positive (FP), false negative (FN), and true negative (TN) of selected studies related to acute cholecystitis, acute pancreatitis, small bowel obstruction, pancreatic cysts, gallbladder adenomyomatosis, and renal colic. Results: Pooling results of the systematic review depicts that in the recent decade, researchers were more concerned with conducting retrospective studies (60%) as compared to prospective studies (40%). Results revealed that 53% of studies were conducted in the United States and other regions which discovered the high incidence of disease in these areas. Only 33% of studies observed the TN, FN, FP, and TP values, whereas the overall sensitivity and specificity of CT was greater than ultrasonography in RUQ pain. Conclusion: CT was statistically and significantly better for the diagnosis of RUQ pain than US but was considered for secondary imaging modality and it was mostly used with those negative of inconclusive ultrasonographic results. While US was used as a primary imaging modality because of its ease of availability, low cost, safe (no ionizing radiations) and convenient handling.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com