Muhammad Bilal, Zafar Ali, Nadira Mamoon.
Dermatofibrosarcoma protuberans of breast- histopathologist\'s perspective.
Pak J Pathol Jan ;31(4):125-7.

Dermatofibrosarcoma protuberans (DFSP) is a rare spindle cell skin tumor mostly located in the dermis and infiltrating into the subcutaneous fat. Breast is a rare site of involvement although trunk and extremities represent the most frequently involved areas. Differentiation from other entities such as a Leiomyoma is important as this lesion requires adequate margin clearance to prevent recurrence. We present case of a young lady that was clinically considered a fibroadenoma and was initially excised accordingly. Histopathology revealed a spindle cell tumor arranged in storiform pattern. Immunohistochemistry revealed a strong positivity for CD34 immunomarker while negative for other markers applied. This report stresses on the diagnostic aspect of DFSP. Key words: Dermatofibrosarcoma Protuberans, Storiform pattern, Immunohistochemistry.

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