Zeeshan Khan, Saadia Khaleeq, Abaid-ur Rehman, Aasam Maan, Umer Farooq, Amjad Nadeem.
Comparison Between Paracetamol Vs Voltral Suppositories for Post Operative Pain in Gynaecological Procedures.
Esculapio J Services Inst Med Sci Jan ;17(2):192-5.

Objective: To compare intravenous paracetamol vs Voltral (Diclofenac) suppositories for post operative pain in gynaecological procedures. Methods: This was a non randomized controlled trial that was carried out at Department of Anaesthesiology, Sheikh Zayed Hospital, Rahim Yar Khan during 01-07-2019 to 31-12-2019 in which all female cases with age range of 20 to 60 year undergoing any gynaecological surgery requiring general anaesthesia were included. The cases were divided into two equal groups and anesthesia was offered in standard doses. Just before reversal the cases in group A were given intravenous paracetamol in a dose of 1 gm stat and then at 8- hour interval and those in group B were offered diclofenac suppositories in a dose of 50 mg twice a day, 12 hours apart. The pain was assessed at 4,8,12 and 24 hours and was labelled on visual analogue scale (VAS). Results: In this study there were 62 cases (31 in each group). The mean age in group A and B was 45.41+-10.21 vs 48.12+-11.13 years with p= 0.47. Mean duration of surgery in both groups was 57.51+-15.23 vs53.11+-14.79 minutes with p= 0.81. There was no significant difference in mean pain score at 4 and 8 hours with p= 0.91 and 0.81 respectively in group A and B. Mean pain score was 4.43+-1.67 vs 3.21+-1.09 with p= 0.01 at 12 and 4.57+-1.71 vs 3.34+-1.27 at 24 hours in group A and B with p values of 0.01 each. Mean time taken for rescue analgesia was 9.13+-2.11 in group A and 13.11+-1.23 hours in group B with p= 0.001. Conclusion; Voltral (Diclofenac sodium) suppositories are better than paracetamol infusion in controlling pain after gynecological surgeries and this difference is significantly better at 12 and 24 hours.

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