Musarrat Jabeen Babar, Mir Hassan Khan.
A two way action of Progesterone in fertility management.
J Postgrad Med Inst Jan ;17(2):231-4.

Objective: To study the role of progesterone in the treatment of amenorrhoea and as a contraceptive. Material and Methods: 120 females having secondary amenorrhoea were treated with 100 mg of progesterone each. In the second group of 120 female having normal menstrual cycle were also given a dose of 100 mg of progesterone. Results: Out of 120 amenorrhoeic patients, progesterone in a dose of 100 mg induced menstruation in 85 (70.8%) cases. The same dose of the hormone on the other hand prevented fertility in the group contraception was required. Conclusion: Hence, we suggest therapy of progesterone with normal level of estradiol and in the first attempt before histopathological examination of uterus for group A and low dose of the drug for group B of fertile women.

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