Agha Shabbir Ali.
Incidence of early Hypocalcemia and role of oral calcium with 1-Alpha Vit D drops in stressed Neonates.
Pak Paed J Jan ;22(4):153-9.

In this prospective study 80 neonates, twenty in each group from IDM, prematures, birth asphyxia (study group; 60 newborn) and normal (20) as controls were studied In study group 36/60 (60%) were found to be hypocalcemic (NHC). Premature babies showed the highest incidence of hypocalcemia and lowest mean serum calcium levels (6.2 ± 0.5 mg/dl). In this study 100% of diabetic mothers were multigravida while 69% of premature were from primi mothers. In IDMs mean weight (4,600 gin ± 65) was higher in hypocalcemic infants than in normocalcemic (3.700 gm ± 44). In premature babies birth weight was lower in hypocalcemic titan in normocalcemic (1.400 gm vs 1.700 gm). Serum phosphorus was consistently high in all stressed hypocalcemics while significantly low total serum protein was found only in premature babies (4.3 gm ± 0.4 vs 5.5 gm ± 0.8). Maternal calcium level was not found to be significant regarding early neonatal hypocalcemia. Hypotonia of prematures (76%) convulsions of asphyxiated newborn (55%) and jitteriness in IDMs (41%) were predominant clinical features. Use of 1-alpha vit-D drops plus oral calcium in asymptomatic hypocalcemic stressed neonates was found to be effective in rapid restoration of normal scrum calcium

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