Sara Mariyum, Amjad Iqbal, Seher Obaid, Munazza Khattak, Khadija Mariyum, Khola Mariyum.
Glycated Hemoglobin Level and Clinical Parameters of Periodontal Disease in Type 2 Diabetes Mellitus.
Adv Basic Med Sci Jan ;5(2):31-4.

Objective To correlate between Glycated Hemoglobin (HbA1c) level and clinical parameters of Periodontal Disease in Type 2 Diabetes Mellitus (T2DM) patients. Methodology : This comparative study was performed from November 2015 to May 2016 in Peshawar. A total of 56 participants suffering from T2DM and periodontal disease were included in the study. All participants were examined for periodontitis by using four parameters Wiesbaden -Germany ' kit. SPSS version 20 was used for data analysis. Results Among 56 subjects, 39.3% had good glycemic control with HbA1c in the range of 6.1-7.0, whereas 60.7% had uncontrolled diabetes with HbA1c of more than 7.0. In terms of Papillary Bleeding Index (PBI) score, the controlled (HbA1c =6.1-7.0) and uncontrolled diabetes groups (HbA1c>7) differed significantly (Chi-Square test p=0.013). Similarly, both the groups differed significantly in terms of Mean Periodontal Disease Index (PDI) (p=0.038, at a significant level of p<0.05) and Periodontal Pocket Depth (PPD) (p-value measured by the t-test p=0.022). Mean number of missing teeth due to periodontal disease was noted as 4.88+-1.42 in the uncontrolled diabetes group and 2.82+-1.26 in controlled diabetes (p= 0.29). A strong significant positive correlation of HbA1c level with PBI (rs=0.595), PDI (rs=0.578) and PPD (rs=0.680) was found. However, a weak but significant correlation (rs=0.289, p=0.041) was also found between HbA1c level and the number of lost teeth due to periodontal disease. Conclusion We concluded that significant correlation exists between Glycated Hemoglobin (HbA1c) level and clinical parameters of Periodontal Disease in Type 2 Diabetics. Keywords: Type 2 Diabetics, Periodontal disease, Glycated hemoglobin

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com