Sudhair Alam, Arshad Khan, Muhammad Sajjad, Abdul Aziz Khan, Ehtisham Ahmad, Adil Ihsan.
Prevalence and distribution of intracranial aneurysms in patients with spontaneous subarachnoid hemorrhage in Hazara division, Pakistan.
Gomal J Med Sci Jan ;20(3):147-53.

Background: Ruptured cerebral aneurysm is the most frequent cause of spontaneous subarachnoid hemorrhage (SAH). The objectives of this study were to determine the prevalence of intracranial aneurysms and their distribution by sex, age groups, number and location in patients with spontaneous SAH in Hazara Division, Pakistan. Materials & Methods: This cross-sectional study was conducted at Department of Neurosurgery, Ayub Medical College, Abbottabad, Pakistan from July 01, 2017 to June 30, 2021. A sample of 119 patients with spontaneous SAH was selected. Patients with history of head trauma and bleeding disorders were excluded. Presence of intracranial aneurysms was a research variable, while sex, age groups, and number and location of aneurysms were demographic variables; all on nominal scale were analyzed by count and percentage with 95%CI. Results: The sample of 119 patients included 50 (42%) men & 69 (58%) women, and 55 (36%) patients in 20-40 & 64 (54%) in 41-69 years. Mean age was 42.51±9.287 years. Prevalence of intracranial aneurysms in spontaneous SAH was 90 (75.63%). Prevalence was similar in men 38 (31.93%) & women 52 (43.70%, and in age group 20-40 years 42 (35.29%) & 41-60 years 48 (40.34%). The prevalence of single aneurysms 86 (72.27%) was higher than multiple aneurysms four (3.36%). Location of aneurysms was similar 43 (36.14%) in middle cerebral artery and 42 (35.29%) in anterior cerebral artery including anterior communicating artery, followed by five (4.20%) in posterior circulation. Conclusion: In our population, prevalence of intracranial aneurysms in spontaneous SAH was 75.63%. Prevalence was similar in men and women, and in age group 20-40 and 41-60 years. Prevalence of single aneurysms was higher than multiple aneurysms. Location of aneurysms was similar in middle cerebral artery and anterior cerebral artery (including anterior communicating artery), followed by posterior circulation.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com