Rohan Qamar, Khalid Mahmood, Narisa Pervaiz, Romassa Javed, Faheem Sher, Ibrahim Tufail.
Comparative study on Incidence of Post-operative Wound Infection in Diabetic vs Non-diabetic patients in Clean Surgical Procedure.
Pak J Med Res Jan ;62(1):14-8.

Background: Diabetes mellitus is associated with a theoretical increase in risk of development of post-operative infections; however, literature on the subject is conflicted, with some studies negating the effect of high blood sugar on the development of surgical wound site complications. Objectives: To compare the complications of ventral hernia repair in diabetics versus non-diabetics in terms of frequency of surgical site infection, seroma and haematoma formation Study type, settings & duration: A prospective cohort study conducted Department of General Surgery, Combined Military Hospital, Rawalpindi from November 2019 to December 2020.    Methodology:  A total of 182 patients (91 in each group) diagnosed with a ventral abdominal hernia who met the sample selection criteria were included. Patients who were diabetic were placed in Group A, while Group B patients were non-diabetic. All patients were followed up for surgical site infection, seroma and haematoma formation. Data was analyzed using SPSS 26.0.   Results: The mean age of patients was 46.54±10.58 years (range 25-70 years). The patients included 113 females (62.1%) and 69 males (37.9%). A total of 9 (9.9%) patients developed surgical site infections in Group A versus 2 (2.2%) in Group B, (p=0.029). Seroma formation was seen in 4 (4.4%) patients of Group A versus 2 (2.2%) Group B patients, p=0.406. One (1.1%) case from each group developed haematomas, (p=1.000). The relative risk ratios in diabetics for developing surgical site infections, seromas and haematomas were RR: 4.9 (CI 95% 1.03 – 23.3), RR: 2.1 (CI 95% 0.37 – 11.5) ........

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